HLA Class II Alleles in Long-Standing Alopecia Totalis/Alopecia Universalis and Long-Standing Patchy Alopecia Areata Differentiate These Two Clinical Groups
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چکیده
منابع مشابه
Transient Efficacy of Tofacitinib in Alopecia Areata Universalis
Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, ...
متن کاملA mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis.
Alopecia areata is among the most prevalent autoimmune diseases, yet compared with other autoimmune conditions, it is not well studied. This in part results from limitations in the C3H/HeJ mouse and DEBR rat model systems most commonly used to study the disease, which display a low frequency and late onset. We describe a novel high-incidence model for spontaneous alopecia areata. The 1MOG244 T ...
متن کاملAlopecia Areata (AA, Patchy Hair Loss) — Causes and Treatment
Alopecia areata is a non-scarring hair loss disorder that can occur in any part of the body, ranging from a small patch to complete loss of hair, without significant age or sex predisposition. Although the exact etiology is unknown, several patient-specific genetic, immunological, and environmental factors have been implicated. The underlying pathology is probably peribulbar infiltration of CD4...
متن کاملAlopecia Areata (AA, Patchy Hair Loss) — Causes and Treatment
Alopecia areata is a non-scarring hair loss disorder that can occur in any part of the body, ranging from a small patch to complete loss of hair, without significant age or sex predisposition. Although the exact etiology is unknown, several patient-specific genetic, immunological, and environmental factors have been implicated. No universally effective treatment exists, although topical or intr...
متن کاملAlopecia Areata (AA, Patchy Hair Loss) — Causes and Treatment
Alopecia areata is a non-scarring hair loss disorder that can occur in any part of the body, ranging from a small patch to complete loss of hair, without significant age or sex predisposition. Although the exact etiology is unknown, several patient-specific genetic, immunological, and environmental factors have been implicated. The underlying pathology is probably peribulbar infiltration of CD4...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1995
ISSN: 0022-202X
DOI: 10.1038/jid.1995.28